Inaugural Cohort · 2026

Psio

Digital neural architecture for psychedelic-assisted therapy.

DEVIN EFFINGER, PHD · DEVIN@PSIO.APP

Who arrives at psychedelic therapy

People arrive
stuck.

01 · STUCK

Patterns that won't move

Mood, habits, thought loops. In some form or fashion, stuck.

02 · THE SHIFT

Psychedelics shift it

The brain, briefly unbound from rigid circuitry.

03 · THE GLIMPSE

A glimpse of change

For many, the first real shift in years.

Why plasticity alone isn't enough

Psychedelics fade.
Old wiring doesn't.

01 · VARIABLE

Every experience is different

Response varies wildly from person to person.

02 · FADING

The effects fade

The old circuitry takes over again.

03 · MONTHS LATER

The same patterns return

Back to the loops that brought them here.

The solution

Digital neural architecture
across the continuum of psychedelic care.

A closed-loop EEG and brain-training platform.

Muse S Athena wearable EEG headband, worn during rest — **WEARABLE EEG** · Muse S Athena

01 · BEFORE

Baseline brain data and brain preparation

02 · DURING

In-session breakthrough state data collection

03 · AFTER

Personalized brain training

In the session room

The Clinician App.

The session, made visible.

01Live EEG
Brain activity, displayed in real time.
02Session workflow
Dosing, notes, and vitals in one screen.
03Moments, marked
Key moments tagged as they happen.

Live EEG data in the clinician app — **LIVE EEG** · band activity and raw signal, in session

The clinician app, live

IN THE SESSION ROOM

● CLINICIAN APP LIVE SESSION

After the session

The Clinic Dashboard.

Every session becomes data.

01Clinic-wide view
Every client, every session, in one place.
02Session brain data
Band power across the session, moments marked.
03Ready for review
Analyzed in the dashboard, minutes after the session.

Session brain data in the clinic dashboard — **SESSION BRAIN DATA** · band power across the session, moments marked

The clinic dashboard, live

EVERY CLIENT · EVERY SESSION

CLINIC DASHBOARD PSIO.APP

At home, between sessions

The Client App.

The work continues at home.

01Check in
A few quiet minutes to start each day.
02Train
Guided neurofeedback, minutes a day.
03See the signal
Progress the client can watch over time.

A daily session

MINUTES A DAY

Versus the alternatives

A first-of-its-kind approach,
rooted in the science.

Built by a team spanning neuropharmacology, psychiatry, nursing, and tech.

01 · CURRENT PRACTICE

Care guided by self-report

Observation and questionnaires, without physiological data.

02 · SESSION TOOLS & EHRS

Documentation, not measurement

They capture what was said, not what changed in the brain.

03 · CONVENTIONAL NEUROFEEDBACK

Not designed for psychedelic care

Existing systems were built for a different clinical setting.

OUR APPROACH

Psychedelic therapy is a neuroplastic event. An opportunity to carve new pathways.

PREPARE → MONITOR → CAPTURE → TRACK → TRAIN

Our focus right now is collecting data

Where we are
today.

Usage · Live 5 psilocybin clients, sessions run on the platform

Pipeline · Committed 3 pilot sites committed

Two ketamine providers. A Denver healing center.

Revenue · First 1 paying neurofeedback client, our first

SIGNAL · DETECTED

Brain-function changes detected around breakthrough moments.

Our priorities for the next six months

Build the datasets.
Strengthen the foundation.

A scientific base that lets the platform scale, and that others can't easily replicate.

01 · PLATFORM

Strengthen the platform

Engineering for reliability at larger scale.

02 · BASELINE

Build the normative dataset

qEEG analysis on commercial headsets.

03 · BIOMARKERS

Predict treatment outcomes

An EEG dataset for biomarker discovery. NIDA SBIR.

WHY IT MATTERS

Maximize what a single dose can do.

As psychedelic therapy enters mainstream medicine: insurance reimbursement, veterans programs, standard of care.

Questions?